Publications

ApoE isoforms differentially regulate neuronal membrane proteasomes to shift the threshold for pathological aggregation of endogenous Tau
Paradise V, Sabu M, Bafia J, Sharif NA, Nguyen C, Dhanraj Mukim R, Wang X, Fu J, Ndubisi J, Maldonado G, Strickland M, Figueroa H, Almeida D, Hyman BT, Holtzman DM, Nuriel T, Ramachandran KV
BioRxiv 2022

Neuronal membrane proteasomes homeostatically regulate neural circuit activity in vivo and are required for learning-induced behavioral plasticity
He HH, Ramachandran KV, McLain N, Faulkner R, Ahsan A, Bera R, Margolis SS, Cline HT
BioRxiv 2022

Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome.
Ramachandran KV, Fu JM, Schaffer TB, Na CH, Delannoy M, Margolis SS.
Molecular Cell. 2018 Jul 5;71(1):169-177.e6. doi: 10.1016/j.molcel.2018.06.013.

A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function.
Ramachandran KV, Margolis SS.
Nature Struct Mol Biol. 2017 Apr;24(4):419-430. doi: 10.1038/nsmb.3389.
Cover article

In Depth | Neuroscience
Is the cell’s garbage disposal sending messages?
Leslie M.
Science. 2017 Mar 31; 355(6332):1361. doi: 10.1126/science.355.6332.1361.

Coordinate Regulation of Stem Cell Competition by Slit-Robo and JAK-STAT Signaling in the Drosophila Testis   Stine RR., Greenspan, LJ., Ramachandran, KV. and Matunis, EL.
PLoS Genetics 2014, 10(11):e1004713. PMCID: PMC4222695.

Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development Ramachandran, KV., Hennessey, JA, Barnett, AS., Yin, X, Stadt, HA., Foster, E., Shah, RA., Yazawa M., Dolmetsch RE., Kirby ML., Pitt GS. Journal of Clinical Investigation 123, no. 4 (April 2013): 1638–46. https://doi.org/10.1172/JCI66903